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Revised Role of Glycosaminoglycans in TAT Protein Transduction Domain-mediated Cellular Transduction

Cellular uptake of the human immunodeficiency virus TAT protein transduction domain (PTD), or cell-penetrating peptide, has previously been surmised to occur in a manner dependent on the presence of heparan sulfate proteoglycans that are expressed ubiquitously on the cell surface. These acidic polys...

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Detalles Bibliográficos
Autores principales: Gump, Jacob M., June, Ronald K., Dowdy, Steven F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801275/
https://www.ncbi.nlm.nih.gov/pubmed/19858185
http://dx.doi.org/10.1074/jbc.M109.021964