Cargando…

Evolution of antibody landscape and viral envelope escape in an HIV-1 CRF02_AG infected patient with 4E10-like antibodies

BACKGROUND: A minority of HIV-1 infected individuals develop broad cross-neutralizing (BCN) plasma antibodies that are capable of neutralizing a spectrum of virus variants belonging to different HIV-1 clades. The aim of this study was to identify the targeted epitopes of an individual with BCN plasm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dieltjens, Tessa, Heyndrickx, Leo, Willems, Betty, Gray, Elin, Van Nieuwenhove, Lies, Grupping, Katrijn, Vanham, Guido, Janssens, Wouter
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801487/ https://www.ncbi.nlm.nih.gov/pubmed/20003438 http://dx.doi.org/10.1186/1742-4690-6-113

Ejemplares similares

P04-34. Identification of 4E10-like antibodies in plasma of an HIV-1 CRF02_AG infected patient with broad neutralizing activity using peptide phage libraries
por: Dieltjens, T, et al.
Publicado: (2009)

Contrasting antibody responses to intrasubtype superinfection with CRF02_AG
por: Courtney, Colleen R., et al.
Publicado: (2017)

Refined identification of neutralization-resistant CRF02_AG viruses and their sensitivity to anti-MPER neutralizing antibodies
por: Jacob, RA, et al.
Publicado: (2012)

P12-11. Resistance to the CD4 mimetic mini protein M48-U1 induces changes in a highly conserved region on the HIV-1 gp120 envelope protein
por: Grupping, K, et al.
Publicado: (2009)

Gag P2/NC and pol genetic diversity, polymorphism, and drug resistance mutations in HIV-1 CRF02_AG- and non-CRF02_AG-infected patients in Yaoundé, Cameroon
por: Teto, Georges, et al.
Publicado: (2017)

The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness
por: Njai, Harr F, et al.
Publicado: (2006)

Identification of Mimotopes with Diagnostic Potential for Trypanosoma brucei gambiense Variant Surface Glycoproteins Using Human Antibody Fractions
por: Van Nieuwenhove, Liesbeth, et al.
Publicado: (2012)

MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency
por: Grupping, Katrijn, et al.
Publicado: (2012)

Phylodynamic analysis of HIV-1 subtypes B, C and CRF 02_AG in Senegal
por: Nascimento, Fabrícia F., et al.
Publicado: (2020)

Broad Antibody Mediated Cross-Neutralization and Preclinical Immunogenicity of New Codon-Optimized HIV-1 Clade CRF02_AG and G Primary Isolates
por: Agwale, Simon M., et al.
Publicado: (2011)

Characterization of Neutralizing Profiles in HIV-1 Infected Patients from whom the HJ16, HGN194 and HK20 mAbs were Obtained
por: Balla-Jhagjhoorsingh, Sunita S., et al.
Publicado: (2011)

HIV-1 CRF 02 AG polymerase genes in Southern Ghana are mosaics of different 02 AG strains and the protease gene cannot infer subtypes
por: Sagoe, Kwamena W, et al.
Publicado: (2009)

A Prime-Boost Immunization Strategy with Vaccinia Virus Expressing Novel gp120 Envelope Glycoprotein from a CRF02_AG Isolate Elicits Cross-Clade Tier 2 HIV-1 Neutralizing Antibodies
por: Calado, Rita, et al.
Publicado: (2020)

Antibody responses to V2 loop are induced by CRF01_A E and not Clade B envelopes
por: Karasavvas, N, et al.
Publicado: (2012)

Spatiotemporal Characteristics of the Largest HIV-1 CRF02_AG Outbreak in Spain: Evidence for Onward Transmissions
por: Kostaki, Evangelia-Georgia, et al.
Publicado: (2019)

Functional analysis of a monoclonal antibody reactive against the C1C2 of Env obtained from a patient infected with HIV-1 CRF02_AG
por: Md Zahid, Hasan, et al.
Publicado: (2021)

The N276 Glycosylation Site Is Required for HIV-1 Neutralization by the CD4 Binding Site Specific HJ16 Monoclonal Antibody
por: Balla-Jhagjhoorsingh, Sunita S., et al.
Publicado: (2013)

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies
por: Kikawa, Caroline, et al.
Publicado: (2023)

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies
por: Kikawa, Caroline, et al.
Publicado: (2023)

Genetic Characteristics, Coreceptor Usage Potential and Evolution of Nigerian HIV-1 Subtype G and CRF02_AG Isolates
por: Ajoge, Hannah O., et al.
Publicado: (2011)

Performance of Xpert HIV-1 viral load test in Senegal: a country of high circulation of CRF02_AG
por: Sène, Pauline Yacine, et al.
Publicado: (2022)

High-Level Drug-Resistant Mutations among HIV-1 Subtype A6 and CRF02_AG in Kazakhstan
por: Sanaubarova, Ainur, et al.
Publicado: (2023)

HJ16 induced resistant virus displays rare natural mutation highlighting the conserved nature of this new CD4bs epitope
por: Balla-Jhagihoorsingh, Sunita S, et al.
Publicado: (2011)

In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors
por: Ni, Xiaoju, et al.
Publicado: (2012)

Circulation of HIV-1 CRF02_AG among MSM Population in Central Italy: A Molecular Epidemiology-Based Study
por: Giuliani, Massimo, et al.
Publicado: (2013)

Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies
por: Kuriakose Gift, Syna, et al.
Publicado: (2023)

Characterization of a novel HIV-1 circulating recombinant form, CRF91_cpx, comprising CRF02_AG, G, J, and U, mostly among men who have sex with men
por: Topcu, Cicek, et al.
Publicado: (2022)

Characterization of HIV-1 CRF02_AG/A3/G unique recombinant forms identified among children in Larkana, Pakistan
por: Rashid, Abdur, et al.
Publicado: (2023)

P09-02. Selection pressure of neutralizing antibodies and viral escape continues in late stages of the disease
por: Rusert, P, et al.
Publicado: (2009)

M48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding
por: Selhorst, Philippe, et al.
Publicado: (2013)

Near full genome characterization of HIV‐1 unique recombinant forms in Cameroon reveals dominant CRF02_AG and F2 recombination patterns
por: Banin, Andrew N, et al.
Publicado: (2019)

Phylogeny of partial gag, pol and env genes show predominance of HIV-1G and CRF02_AG with emerging recombinants in south-eastern Nigeria
por: Udeze, Augustine O., et al.
Publicado: (2020)

Interaction analysis of statistically enriched mutations identified in Cameroon recombinant subtype CRF02_AG that can influence the development of Dolutegravir drug resistance mutations
por: Mikasi, Sello Given, et al.
Publicado: (2021)

Female Sex Hormones Upregulate the Replication Activity of HIV-1 Sub-Subtype A6 and CRF02_AG but Not HIV-1 Subtype B
por: Nosik, Marina, et al.
Publicado: (2023)

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes
por: Futch, Hunter S., et al.
Publicado: (2019)

Longitudinal Study of Primary HIV-1 Isolates in Drug-Naïve Individuals Reveals the Emergence of Variants Sensitive to Anti-HIV-1 Monoclonal Antibodies
por: Haldar, Bijayesh, et al.
Publicado: (2011)

Frequent CXCR4 tropism of HIV-1 subtype A and CRF02_AG during late-stage disease - indication of an evolving epidemic in West Africa
por: Esbjörnsson, Joakim, et al.
Publicado: (2010)

Epigenetics, N-myrystoyltransferase-1 and casein kinase-2-alpha modulates the increased replication of HIV-1 CRF02_AG, compared to subtype-B viruses
por: Bhargavan, Biju, et al.
Publicado: (2019)

Preventing escape from neutralizing antibodies
por: Brown, Matthew
Publicado: (2020)

Fast Dissemination of New HIV-1 CRF02/A1 Recombinants in Pakistan
por: Chen, Yue, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_87oc4606o2t5qkjesus66la2u2