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Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature

BACKGROUND: Surgical resection remains the gold standard for the treatment of localized adenocarcinoma of the extrahepatic bile ducts. Yet, treatment of loco-regional recurrences is not well defined. CASE PRESENTATION: We present an unusual case of distal adenocarcinoma of the extrahepatic bile duct...

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Autores principales: Rodríguez-Pascual, Jesús, De Vicente, Emilio, Quijano, Yolanda, Pérez-Rodríguez, Francisco, Bergaz, Fernando, Hidalgo, Manuel, Duran, Ignacio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801668/
https://www.ncbi.nlm.nih.gov/pubmed/20003448
http://dx.doi.org/10.1186/1477-7819-7-96
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author Rodríguez-Pascual, Jesús
De Vicente, Emilio
Quijano, Yolanda
Pérez-Rodríguez, Francisco
Bergaz, Fernando
Hidalgo, Manuel
Duran, Ignacio
author_facet Rodríguez-Pascual, Jesús
De Vicente, Emilio
Quijano, Yolanda
Pérez-Rodríguez, Francisco
Bergaz, Fernando
Hidalgo, Manuel
Duran, Ignacio
author_sort Rodríguez-Pascual, Jesús
collection PubMed
description BACKGROUND: Surgical resection remains the gold standard for the treatment of localized adenocarcinoma of the extrahepatic bile ducts. Yet, treatment of loco-regional recurrences is not well defined. CASE PRESENTATION: We present an unusual case of distal adenocarcinoma of the extrahepatic bile ducts that was treated with surgery and relapsed two years later with a solitary recurrence on the tract of a previous Redon drain. In addition, a review of the literature on management of loco regional relapses is presented. CONCLUSIONS: The ideal management of these patients still remains undefined. Decisions are made based on clinical parameters from retrospective series, such as tumor grade, surgical margins or lymph node involvement. Prospective studies, that include molecular and genetic markers, are needed to improve patient selection and outcomes on this population.
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spelling pubmed-28016682010-01-05 Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature Rodríguez-Pascual, Jesús De Vicente, Emilio Quijano, Yolanda Pérez-Rodríguez, Francisco Bergaz, Fernando Hidalgo, Manuel Duran, Ignacio World J Surg Oncol Case report BACKGROUND: Surgical resection remains the gold standard for the treatment of localized adenocarcinoma of the extrahepatic bile ducts. Yet, treatment of loco-regional recurrences is not well defined. CASE PRESENTATION: We present an unusual case of distal adenocarcinoma of the extrahepatic bile ducts that was treated with surgery and relapsed two years later with a solitary recurrence on the tract of a previous Redon drain. In addition, a review of the literature on management of loco regional relapses is presented. CONCLUSIONS: The ideal management of these patients still remains undefined. Decisions are made based on clinical parameters from retrospective series, such as tumor grade, surgical margins or lymph node involvement. Prospective studies, that include molecular and genetic markers, are needed to improve patient selection and outcomes on this population. BioMed Central 2009-12-14 /pmc/articles/PMC2801668/ /pubmed/20003448 http://dx.doi.org/10.1186/1477-7819-7-96 Text en Copyright ©2009 Rodríguez-Pascual et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case report
Rodríguez-Pascual, Jesús
De Vicente, Emilio
Quijano, Yolanda
Pérez-Rodríguez, Francisco
Bergaz, Fernando
Hidalgo, Manuel
Duran, Ignacio
Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title_full Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title_fullStr Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title_full_unstemmed Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title_short Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
title_sort isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: case report and review of the literature
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801668/
https://www.ncbi.nlm.nih.gov/pubmed/20003448
http://dx.doi.org/10.1186/1477-7819-7-96
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