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Paclitaxel inhibits growth, migration and collagen production of human Tenon's fibroblasts—potential use in drug-eluting glaucoma drainage devices

OBJECTIVE/AIM: One of the factors limiting the long-term success of glaucoma drainage devices and traditional filtering surgery is the tendency of bleb encapsulation. Glaucoma shunts present an opportunity of introducing drug-eluting mechanisms for a lasting exposure of the bleb to anti-proliferativ...

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Detalles Bibliográficos
Autores principales: Choritz, Lars, Grub, Jochen, Wegner, Maria, Pfeiffer, Norbert, Thieme, Hagen
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801844/
https://www.ncbi.nlm.nih.gov/pubmed/19898860
http://dx.doi.org/10.1007/s00417-009-1221-4