Cargando…
A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women
Female sex is an independent risk factor for development of torsade de pointes (TdP)-type arrhythmias in both congenital and acquired long QT syndrome (LQTS). In females, QT(c) interval and TdP risk vary during the menstrual cycle and around delivery. Biological experiments including single-cell cur...
Autores principales: | Furukawa, Tetsushi, Kurokawa, Junko, Clancy, Colleen E |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2801855/ https://www.ncbi.nlm.nih.gov/pubmed/20066131 http://dx.doi.org/10.2174/157340308786349507 |
Ejemplares similares
-
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
por: Okada, Jun-ichi, et al.
Publicado: (2015) -
Acute Effects of Sex Steroid Hormones on Susceptibility to Cardiac Arrhythmias: A Simulation Study
por: Yang, Pei-Chi, et al.
Publicado: (2010) -
TdP Incidence in Methoxamine-Sensitized Rabbit Model Is Reduced With Age but Not Influenced by Hypercholesterolemia
por: Nalos, Lukáš, et al.
Publicado: (2021) -
In silico assessment on TdP risks of drug combinations under CiPA paradigm
por: Qauli, Ali Ikhsanul, et al.
Publicado: (2023) -
A patch-clamp study of histamine-secreting cells
Publicado: (1986)