Long-range Oncogenic Activation of IgH/c-myc Translocations by the IgH 3’ Regulatory Region

B cell malignancies, such as human Burkitt’s lymphoma (BL), often harbor translocations that link c-myc or other proto-oncogenes to the immunoglobulin heavy chain locus (IgH)1. The nature of elements that activate oncogenes within such translocations has been a longstanding question. Translocations...

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Detalles Bibliográficos
Autores principales: Gostissa, Monica, Yan, Catherine T., Bianco, Julia M., Cogné, Michel, Pinaud, Eric, Alt, Frederick W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802177/
https://www.ncbi.nlm.nih.gov/pubmed/20010689
http://dx.doi.org/10.1038/nature08633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802177/
https://www.ncbi.nlm.nih.gov/pubmed/20010689
http://dx.doi.org/10.1038/nature08633

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