N-methyl-N-nitrosourea-induced retinal degeneration in mice is independent of the p53 gene

PURPOSE: A single systemic administration of N-methyl-N-nitrosourea (MNU) causes retinal degeneration involving photoreceptor cell loss within 7 days. MNU-induced photoreceptor cell loss is due to apoptosis and is a reliable animal model for human retinitis pigmentosa. The purpose of this study was...

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Detalles Bibliográficos
Autores principales: Yoshizawa, Katsuhiko, Kuwata, Maki, Kawanaka, Ayako, Uehara, Norihisa, Yuri, Takashi, Tsubura, Airo
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802295/
https://www.ncbi.nlm.nih.gov/pubmed/20057907

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