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T cell intrinsic role of Nod2 in promoting type I immunity against Toxoplasma gondii
Nod2 belongs to the (NOD)-like receptor (NLR) family of proteins, which function as intracellular pathogen sensors in innate immune cells. Nod2-deficiency results in an impaired immune response against bacterial pathogens. However, our understanding of how this protein promotes host defense against...
Autores principales: | Shaw, Michael H., Reimer, Thornik, Sánchez-Valdepeñas, Carmen, Warner, Neil, Kim, Yun-Gi, Fresno, Manuel, Nuñez, Gabriel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803073/ https://www.ncbi.nlm.nih.gov/pubmed/19881508 http://dx.doi.org/10.1038/ni.1816 |
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