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A New Paradigm for Antimicrobial Host Defense Mediated by a Nitrated Cyclic Nucleotide
Nitric oxide (NO), produced by inducible NO synthase (iNOS) during infection, plays a crucial role in host defense mechanisms. Salmonella typhimurium infection in mice is associated with excessive production of NO from iNOS as a host defense response. An important cytoprotective and antimicrobial fu...
Autores principales: | Okamoto, Tatsuya, Khan, Shahzada, Oyama, Kohta, Fujii, Shigemoto, Sawa, Tomohiro, Akaike, Takaaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803128/ https://www.ncbi.nlm.nih.gov/pubmed/20104260 http://dx.doi.org/10.3164/jcbn.SR09-70 |
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