The Right Ventricle: Biologic Insights and Response to Disease

Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a limited analysis of the unique and distinguishing physiologic properties of the RV under normal circumstances and in response to p...

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Detalles Bibliográficos
Autores principales: Walker, Lori A, Buttrick, Peter M
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803284/
https://www.ncbi.nlm.nih.gov/pubmed/20066144
http://dx.doi.org/10.2174/157340309787048077
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author Walker, Lori A
Buttrick, Peter M
author_facet Walker, Lori A
Buttrick, Peter M
author_sort Walker, Lori A
collection PubMed
description Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a limited analysis of the unique and distinguishing physiologic properties of the RV under normal circumstances and in response to pathologic insults. This review highlights some of these features and underscores the fact that rational therapy in RV failure should acknowledge this physiology and ought to be chamber specific.
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spelling pubmed-28032842010-01-11 The Right Ventricle: Biologic Insights and Response to Disease Walker, Lori A Buttrick, Peter M Curr Cardiol Rev Article Despite ample evidence that right ventricular function is a critical determinant of the clinical response to a spectrum of cardiovascular diseases, there has been only a limited analysis of the unique and distinguishing physiologic properties of the RV under normal circumstances and in response to pathologic insults. This review highlights some of these features and underscores the fact that rational therapy in RV failure should acknowledge this physiology and ought to be chamber specific. Bentham Science Publishers Ltd. 2009-01 /pmc/articles/PMC2803284/ /pubmed/20066144 http://dx.doi.org/10.2174/157340309787048077 Text en © 2009 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Walker, Lori A
Buttrick, Peter M
The Right Ventricle: Biologic Insights and Response to Disease
title The Right Ventricle: Biologic Insights and Response to Disease
title_full The Right Ventricle: Biologic Insights and Response to Disease
title_fullStr The Right Ventricle: Biologic Insights and Response to Disease
title_full_unstemmed The Right Ventricle: Biologic Insights and Response to Disease
title_short The Right Ventricle: Biologic Insights and Response to Disease
title_sort right ventricle: biologic insights and response to disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803284/
https://www.ncbi.nlm.nih.gov/pubmed/20066144
http://dx.doi.org/10.2174/157340309787048077
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