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Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart

Atrial and brain natriuretic peptides (ANP and BNP, respectively) are cardiac hormones, secretions of which are markedly upregulated during cardiac failure, making their plasma levels clinically useful diagnostic markers. ANP and BNP exert potent diuretic, natriuretic and vasorelaxant effects, which...

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Detalles Bibliográficos
Autores principales: Kishimoto, Ichiro, Tokudome, Takeshi, Horio, Takeshi, Garbers, David L, Nakao, Kazuwa, Kangawa, Kenji
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803288/
https://www.ncbi.nlm.nih.gov/pubmed/20066148
http://dx.doi.org/10.2174/157340309787048068