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Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart
Atrial and brain natriuretic peptides (ANP and BNP, respectively) are cardiac hormones, secretions of which are markedly upregulated during cardiac failure, making their plasma levels clinically useful diagnostic markers. ANP and BNP exert potent diuretic, natriuretic and vasorelaxant effects, which...
Autores principales: | Kishimoto, Ichiro, Tokudome, Takeshi, Horio, Takeshi, Garbers, David L, Nakao, Kazuwa, Kangawa, Kenji |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803288/ https://www.ncbi.nlm.nih.gov/pubmed/20066148 http://dx.doi.org/10.2174/157340309787048068 |
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