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The Binding Properties of Glycosylated and Non-Glycosylated Tim-3 Molecules on CD4(+)CD25(+) T Cells
BACKGROUND: T cell immunoglobulin and mucin domain containing 3 protein (Tim-3) expressed on terminally differentiated Th1 cells plays a suppressive role in Th1-mediated immune responses. Recently, it has been shown that N-glycosylation affects the binding activity of the Tim-3-Ig fusion protein to...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Association of Immunobiologists
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803304/ https://www.ncbi.nlm.nih.gov/pubmed/20107545 http://dx.doi.org/10.4110/in.2009.9.2.58 |