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Heterogeneous SWI/SNF Chromatin Remodeling Complexes Promote Expression of Microphthalmia —Associated Transcription Factor Target Genes in Melanoma

The microphthalmia-associated transcription factor (MITF) promotes melanocyte differentiation and cell cycle arrest. Paradoxically, MITF also promotes melanoma survival and proliferation, acting like a lineage survival oncogene. Thus, it is critically important to understand the mechanisms that regu...

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Detalles Bibliográficos
Autores principales: Keenen, B., Qi, H, Saladi, S.V., Yeung, M., de la Serna, I.L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803337/
https://www.ncbi.nlm.nih.gov/pubmed/19784067
http://dx.doi.org/10.1038/onc.2009.304