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Comparative Docking Assessment of Glucokinase Interactions with its Allosteric Activators
Glucokinase (GK) is expressed in multiple organs and plays a key role in hepatic glucose metabolism and pancreatic insulin secretion. GK could indeed serve as pacemaker of glycolysis and could be an attractive target for type 2 diabetes (T2D). The recent preclinical data of first GK activator RO-28-...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Open
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803441/ https://www.ncbi.nlm.nih.gov/pubmed/20161845 http://dx.doi.org/10.2174/1875397300802010076 |