2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

BACKGROUND: Past studies have shown that sensitivity of melanoma cells to TRAIL-induced apoptosis is largely correlated with the expression levels of TRAIL death receptors on the cell surface. However, fresh melanoma isolates and melanoma tissue sections express generally low levels of death recepto...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Jiang, Chen Chen, Lavis, Christopher J, Croft, Amanda, Dong, Li, Tseng, Hsin-Yi, Yang, Fan, Tay, Kwang Hong, Hersey, Peter, Zhang, Xu Dong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803449/
https://www.ncbi.nlm.nih.gov/pubmed/20003459
http://dx.doi.org/10.1186/1476-4598-8-122

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