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Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging

The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The...

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Detalles Bibliográficos
Autores principales: Paul, Dominik, Zaitsev, Maxim, Harsan, Laura, Kurutsch, Anja, Splitthoff, Daniel Nico, Hennel, Franciszek, Choli, Morwan, von Elverfeldt, Dominik
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804056/
https://www.ncbi.nlm.nih.gov/pubmed/20069119
http://dx.doi.org/10.1155/2009/946271
Descripción
Sumario:The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The correction procedure was applied to phantom and in vivo imaging of mice and rats at 9.4T using different SE-EPI and DWI-EPI protocols. Results show the significant improvement in image quality for single- and multishot EPI. Using a reduced FOV in the PSF encoding direction clearly reduced the acquisition time for PSF data by an acceleration factor of 2 or 4, without affecting the correction quality.