IRS1 Regulation by Wnt/β-Catenin Signaling and Varied Contribution of IRS1 to the Neoplastic Phenotype

Dysregulation of β-catenin levels and localization and constitutive activation of β-catenin/TCF (T cell factor)-regulated gene expression occur in many cancers, including the majority of colorectal carcinomas and a subset of ovarian endometrioid adenocarcinomas. Based on the results of microarray-ba...

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Detalles Bibliográficos
Autores principales: Bommer, Guido T., Feng, Ying, Iura, Ayaka, Giordano, Thomas J., Kuick, Rork, Kadikoy, Hüseyin, Sikorski, Deanna, Wu, Rong, Cho, Kathleen R., Fearon, Eric R.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804351/
https://www.ncbi.nlm.nih.gov/pubmed/19843521
http://dx.doi.org/10.1074/jbc.M109.060319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804351/
https://www.ncbi.nlm.nih.gov/pubmed/19843521
http://dx.doi.org/10.1074/jbc.M109.060319

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