Cargando…

Reduced expression of cenp-e in human hepatocellular carcinoma

BACKGROUND: CENP-E, one of spindle checkpoint proteins, plays a crucial role in the function of spindle checkpoint. Once CENP-E expression was interrupted, the chromosomes can not separate procedurally, and may result in aneuploidy which is a hallmark of most solid cancers, such as hepatocellular ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zijie, Ling, Kang, Wu, Xia, Cao, Ju, Liu, Bin, Li, Suyan, Si, Qiong, Cai, Yan, Yan, Chen, Zhang, Yan, Weng, Yaguang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804602/ https://www.ncbi.nlm.nih.gov/pubmed/20021663 http://dx.doi.org/10.1186/1756-9966-28-156

Ejemplares similares

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways
por: Bancroft, James, et al.
Publicado: (2015)

CENP-E falls off
por: Wells, William A.
Publicado: (2001)

CENP-E goes fishing for microtubules
por: Leslie, Mitch
Publicado: (2008)

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly
por: Shono, Nobuaki, et al.
Publicado: (2015)

BubR1 checks in with CENP-E
por: LeBrasseur, Nicole
Publicado: (2003)

Reconstitution of an active human CENP-E motor
por: Craske, Benjamin, et al.
Publicado: (2022)

Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore
por: Tian, Tian, et al.
Publicado: (2018)

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores
por: Wu, Min, et al.
Publicado: (2019)

SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores
por: Li, Teng, et al.
Publicado: (2016)

Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly
por: Liu, Xu, et al.
Publicado: (2019)

Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres
por: Alonso, Alicia, et al.
Publicado: (2007)

Stable complex formation of CENP-B with the CENP-A nucleosome
por: Fujita, Risa, et al.
Publicado: (2015)

CENP-E Function at Kinetochores Is Essential for Chromosome Alignment
por: Schaar, B.T., et al.
Publicado: (1997)

Characterization of the Kinetochore Binding Domain of CENP-E Reveals Interactions with the Kinetochore Proteins CENP-F and hBUBR1
por: Chan, G.K.T., et al.
Publicado: (1998)

CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance
por: Hu, Liqiao, et al.
Publicado: (2023)

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases
por: Ciossani, Giuseppe, et al.
Publicado: (2018)

Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells
por: Yoshizawa, Koya, et al.
Publicado: (2023)

Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N
por: Carroll, Christopher W., et al.
Publicado: (2009)

Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres
por: Xiao, Hua, et al.
Publicado: (2017)

Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-T
por: Rago, Florencia, et al.
Publicado: (2015)

Histone-fold centromere protein W (CENP-W) is associated with the biological behavior of hepatocellular carcinoma cells
por: Zhou, Ziliang, et al.
Publicado: (2020)

Kinesin-7 CENP-E regulates chromosome alignment and genome stability of spermatogenic cells
por: She, Zhen-Yu, et al.
Publicado: (2020)

Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts
por: Kullmann , Frank, et al.
Publicado: (1999)

Leaving no-one behind: how CENP-E facilitates chromosome alignment
por: Craske, Benjamin, et al.
Publicado: (2020)

CENP-A Regulation and Cancer
por: Renaud-Pageot, Charlène, et al.
Publicado: (2022)

Clinical Significance of CENP-H Expression in Uterine Cervical Cancer
por: Weng, Mei-ying, et al.
Publicado: (2012)

The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts
por: Krizaic, Iva, et al.
Publicado: (2015)

CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly
por: Otake, Koichiro, et al.
Publicado: (2020)

Dynamic cell cycle–dependent phosphorylation modulates CENP-L–CENP-N centromere recruitment
por: Navarro, Alexandra P., et al.
Publicado: (2022)

Upregulation of CENP-H in tongue cancer correlates with poor prognosis and progression
por: Liao, Wen-Ting, et al.
Publicado: (2009)

Low expression of spindle checkpoint protein, Cenp-E, causes numerical chromosomal abnormalities in HepG-2 human hepatoma cells
por: LIU, BIN, et al.
Publicado: (2015)

A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity
por: Ohashi, Akihiro, et al.
Publicado: (2015)

Does FANCA Assist CENP-E in Architectural Organization of Chromosomes at Spindle Equator?
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2018)

Transcriptomic Changes Following Partial Depletion of CENP-E in Normal Human Fibroblasts
por: Cilluffo, Danilo, et al.
Publicado: (2021)

A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona
por: Wu, Jingchao, et al.
Publicado: (2023)

CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly
por: Moree, Ben, et al.
Publicado: (2011)

Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis
por: Kwenda, Lucretia, et al.
Publicado: (2016)

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization
por: Watanabe, Reito, et al.
Publicado: (2019)

Mitosis-related gene CENP-U as a potential biomarker in malignancy
por: Shao, Changjian, et al.
Publicado: (2021)

S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway
por: Wu, Rui, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lpugja69pjbrct0v6e4o36d8h4