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Overexpression of the ATP binding cassette gene ABCA1 determines resistance to Curcumin in M14 melanoma cells

BACKGROUND: Curcumin induces apoptosis in many cancer cells and it reduces xenograft growth and the formation of lung metastases in nude mice. Moreover, the plant derived polyphenol has been reported to be able to overcome drug resistance to classical chemotherapy. These features render the drug a p...

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Detalles Bibliográficos
Autores principales: Bachmeier, Beatrice E, Iancu, Cristina M, Killian, Peter H, Kronski, Emanuel, Mirisola, Valentina, Angelini, Giovanna, Jochum, Marianne, Nerlich, Andreas G, Pfeffer, Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804606/
https://www.ncbi.nlm.nih.gov/pubmed/20030852
http://dx.doi.org/10.1186/1476-4598-8-129