Developmental iodine deficiency resulting in hypothyroidism reduces hippocampal ERK1/2 and CREB in lactational and adolescent rats

BACKGROUND: Developmental iodine deficiency (ID) leads to inadequate thyroid hormone that impairs learning and memory with an unclear mechanism. Here, we show that hippocampal extracellular signal-regulated kinase (ERK1/2) and cAMP response element-binding protein (CREB) are implicated in the impair...

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Detalles Bibliográficos
Autores principales: Dong, Jing, Liu, Wanyang, Wang, Yi, Hou, Yi, Xi, Qi, Chen, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804698/
https://www.ncbi.nlm.nih.gov/pubmed/20021662
http://dx.doi.org/10.1186/1471-2202-10-149

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