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ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
BACKGROUND: Cancer cells display widespread changes in DNA methylation that may lead to genetic instability by global hypomethylation and aberrant silencing of tumor suppressor genes by focal hypermethylation. In turn, altered DNA methylation patterns have been used to identify putative tumor suppre...
Autores principales: | Götze, Silke, Feldhaus, Valeska, Traska, Thilo, Wolter, Marietta, Reifenberger, Guido, Tannapfel, Andrea, Kuhnen, Cornelius, Martin, Dirk, Müller, Oliver, Sievers, Sonja |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804712/ https://www.ncbi.nlm.nih.gov/pubmed/20017917 http://dx.doi.org/10.1186/1471-2407-9-447 |
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