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Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma

BACKGROUND: Trimethylation of lysine 27 on histone H3 (H3K27me3) by enhancer of zeste homolog 2 (EZH2) is an epigenetic mark that mediates gene silencing. EZH2 is overexpressed and correlates with poor prognosis in many cancers. However, the clinical implication of H3K27me3 in human malignancies has...

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Detalles Bibliográficos
Autores principales:	He, Li-Ru, Liu, Meng-Zhong, Li, Bin-Kui, Rao, Hui-Lan, Liao, Yi-Ji, Guan, Xin-Yuan, Zeng, Yi-Xin, Xie, Dan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804715/ https://www.ncbi.nlm.nih.gov/pubmed/20028503 http://dx.doi.org/10.1186/1471-2407-9-461

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