STING an Endoplasmic Reticulum Adaptor that Facilitates Innate Immune Signaling

We report here the identification, following expression cloning, of a molecule, STING (STimulator of INterferon Genes) that regulates innate immune signaling processes. STING, comprising 5 putative transmembrane (TM) regions, predominantly resides in the endoplasmic reticulum (ER) and is able to act...

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Detalles Bibliográficos
Autores principales: Ishikawa, Hiroki, Barber, Glen N.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804933/
https://www.ncbi.nlm.nih.gov/pubmed/18724357
http://dx.doi.org/10.1038/nature07317

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