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EBNA3C interacts with Gadd34 and counteracts the unfolded protein response

EBNA3C is an EBV-encoded nuclear protein, essential for proliferation of EBV infected B-lymphocytes. Using EBNA3C amino acids 365-545 in a yeast two hybrid screen, we found an interaction with the Growth Arrest and DNA-damage protein, Gadd34. When both proteins are overexpressed, Gadd34 can interact...

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Detalles Bibliográficos
Autores principales: Garrido, Jose L, Maruo, Seijii, Takada, Kenzo, Rosendorff, Adam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805635/
https://www.ncbi.nlm.nih.gov/pubmed/20040105
http://dx.doi.org/10.1186/1743-422X-6-231