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Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients

BACKGROUND: Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation properties of stem cell-like populations within malignancies. We aim to identify...

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Detalles Bibliográficos
Autores principales: Gallagher, Michael F, Flavin, Richard J, Elbaruni, Salah A, McInerney, Jamie K, Smyth, Paul C, Salley, Yvonne M, Vencken, Sebastian F, O'Toole, Sharon A, Laios, Alexandros, Lee, Mathia YC, Denning, Karen, Li, Jinghuan, Aherne, Sinead T, Lao, Kai Q, Martin, Cara M, Sheils, Orla M, O'Leary, John J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805659/
https://www.ncbi.nlm.nih.gov/pubmed/20015364
http://dx.doi.org/10.1186/1757-2215-2-19