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Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

BACKGROUND: Hypoxia is associated with increased resistance to chemo- and radiation-therapy. Hyperoxic treatment (hyperbaric oxygen) has previously been shown to potentiate the effect of some forms of chemotherapy, and this has been ascribed to enhanced cytotoxicity or neovascularisation. The aim of...

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Detalles Bibliográficos
Autores principales: Moen, Ingrid, Tronstad, Karl J, Kolmannskog, Odd, Salvesen, Gerd S, Reed, Rolf K, Stuhr, Linda EB
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805681/
https://www.ncbi.nlm.nih.gov/pubmed/20017908
http://dx.doi.org/10.1186/1471-2407-9-446