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Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies

Genome-wide association studies (GWAS) may be biased by population stratification (PS). We conducted empirical quantification of the magnitude of PS among human populations and its impact on GWAS. Liver tissues were collected from 979, 59 and 49 Caucasian Americans (CA), African Americans (AA) and H...

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Detalles Bibliográficos
Autores principales: Hao, Ke, Chudin, Eugene, Greenawalt, Danielle, Schadt, Eric E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805717/
https://www.ncbi.nlm.nih.gov/pubmed/20084173
http://dx.doi.org/10.1371/journal.pone.0008695