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Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies
Genome-wide association studies (GWAS) may be biased by population stratification (PS). We conducted empirical quantification of the magnitude of PS among human populations and its impact on GWAS. Liver tissues were collected from 979, 59 and 49 Caucasian Americans (CA), African Americans (AA) and H...
Autores principales: | Hao, Ke, Chudin, Eugene, Greenawalt, Danielle, Schadt, Eric E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805717/ https://www.ncbi.nlm.nih.gov/pubmed/20084173 http://dx.doi.org/10.1371/journal.pone.0008695 |
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