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Bronchial hyper-responsiveness, subepithelial fibrosis, and transforming growth factor-β(1) expression in patients with long-standing and recently diagnosed asthma

INTRODUCTION: Chronic inflammation in asthmatic airways leads to bronchial hyper-responsiveness (BHR) and the development of structural changes. Important features of remodeling include the formation of subepithelial fibrosis due to increased collagen deposition in the reticular basement membrane. T...

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Detalles Bibliográficos
Autores principales: Tomkowicz, Aneta, Kraus-Filarska, Maria, Bar, Julia, Rabczyński, Jerzy, Jeleń, Michał, Piesiak, Paweł, Fal, Andrzej, Panaszek, Bernard
Formato: Texto
Lenguaje:English
Publicado: Birkhäuser-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805797/
https://www.ncbi.nlm.nih.gov/pubmed/19043669
http://dx.doi.org/10.1007/s00005-008-0044-z