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Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype

BACKGROUND: Tumours contain hypoxic regions that select for an aggressive cell phenotype; tumour hypoxia induces metastasis-associated genes. Treatment refractory patients with metastatic cancer show increased numbers of circulating tumour cells (CTCs), which are also associated with disease progres...

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Detalles Bibliográficos
Autores principales:	Ameri, K, Luong, R, Zhang, H, Powell, A A, Montgomery, K D, Espinosa, I, Bouley, D M, Harris, A L, Jeffrey, S S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805847/ https://www.ncbi.nlm.nih.gov/pubmed/20051957 http://dx.doi.org/10.1038/sj.bjc.6605491

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