Cargando…

Pharmacokinetic and clinical profile of a novel formulation of bosentan in children with pulmonary arterial hypertension: the FUTURE-1 study

AIM: To show equivalent bosentan exposure in paediatric patients with pulmonary arterial hypertension (PAH) when compared with a cohort of historical controls of adult PAH patients using a newly developed paediatric formulation. METHODS: Thirty-six paediatric PAH patients were enrolled in this multi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beghetti, Maurice, Haworth, Sheila G, Bonnet, Damien, Barst, Robyn J, Acar, Philippe, Fraisse, Alain, Ivy, Dunbar D, Jais, Xavier, Schulze-Neick, Ingram, Galiè, Nazzareno, Morganti, Adele, Dingemanse, Jasper, Kusic-Pajic, Andjela, Berger, Rolf M F
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Science Inc 2009
Materias:	Paediatric Clinical Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805863/ https://www.ncbi.nlm.nih.gov/pubmed/20002090 http://dx.doi.org/10.1111/j.1365-2125.2009.03532.x

Ejemplares similares

A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE‐3
por: Berger, Rolf M. F., et al.
Publicado: (2017)

Echocardiographic Changes and Long-Term Clinical Outcomes in Pediatric Patients With Pulmonary Arterial Hypertension Treated With Bosentan for 72 Weeks: A Post-hoc Analysis From the FUTURE 3 Study
por: Beghetti, Maurice, et al.
Publicado: (2021)

Clinical perspectives with long-term pulsed inhaled nitric oxide for the treatment of pulmonary arterial hypertension
por: Barst, Robyn J., et al.
Publicado: (2012)

Health outcomes, healthcare use and development in children born into or growing up in single-parent households: a systematic review study protocol
por: Lut, Irina, et al.
Publicado: (2021)

Bosentan monohydrate
por: Kaur, Manpreet, et al.
Publicado: (2012)

Clinical trials in neonates and children: Report of the pulmonary hypertension academic research consortium pediatric advisory committee
por: Adatia, Ian, et al.
Publicado: (2013)

Multicentre, randomised controlled feasibility study to compare a 10-week physiotherapy programme using an interactive exercise training device to improve walking and balance, to usual care of children with cerebral palsy aged 4–18 years: the ACCEPT study protocol
por: Rapson, Rachel, et al.
Publicado: (2022)

Health-related quality of life in congenital heart disease surgery patients in Pakistan: protocol for a mixed-methods study
por: Ladak, Laila Akbar, et al.
Publicado: (2017)

Does family-centred neonatal discharge planning reduce healthcare usage? A before and after study in South West England
por: Ingram, Jenny C, et al.
Publicado: (2016)

Treatment of pediatric pulmonary arterial hypertension: A focus on the NO‐sGC‐cGMP pathway
por: Beghetti, Maurice, et al.
Publicado: (2019)

Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management
por: Rosenzweig, Erika B., et al.
Publicado: (2019)

The Lililwan Project: study protocol for a population-based active case ascertainment study of the prevalence of fetal alcohol spectrum disorders (FASD) in remote Australian Aboriginal communities
por: Fitzpatrick, James P, et al.
Publicado: (2012)

Screening and treatment to reduce severe hyperbilirubinaemia in infants in primary care (STARSHIP): a factorial stepped-wedge cluster randomised controlled trial protocol
por: van der Geest, Berthe A M, et al.
Publicado: (2019)

Better assessment of neonatal jaundice at home (BEAT Jaundice @home): protocol for a prospective, multicentre diagnostic study
por: Westenberg, Lauren E H, et al.
Publicado: (2022)

Cow’s Milk Fat Obesity pRevention Trial (CoMFORT): a primary care embedded randomised controlled trial protocol to determine the effect of cow’s milk fat on child adiposity
por: Vanderhout, Shelley M, et al.
Publicado: (2020)

Studies on the Vitrified and Cryomilled Bosentan
por: Minecka, Aldona, et al.
Publicado: (2021)

INTERGROWTH-21st Project international INTER-NDA standards for child development at 2 years of age: an international prospective population-based study
por: Fernandes, Michelle, et al.
Publicado: (2020)

Watch me grow integrated (WMG-I): protocol for a cluster randomised controlled trial of a web-based surveillance approach for developmental screening in primary care settings
por: Eapen, Valsamma, et al.
Publicado: (2022)

A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy
por: Kefford, Richard F, et al.
Publicado: (2010)

The effect of Bosentan on healing of colonic anastomosis
por: Cetinkaya, Ziya, et al.
Publicado: (2006)

A systematic mapping review of effective interventions for communicating with, supporting and providing information to parents of preterm infants
por: Brett, Jo, et al.
Publicado: (2011)

Pharmacokinetic research in children: an analysis of registered records of clinical trials
por: Viergever, Roderik F, et al.
Publicado: (2011)

A retrospective cross-sectional study of risk factors and clinical spectrum of children admitted to hospital with pandemic H1N1 influenza as compared to influenza A
por: Morris, Shaun K, et al.
Publicado: (2012)

Comparing media and family predictors of alcohol use: a cohort study of US adolescents
por: Stoolmiller, Mike, et al.
Publicado: (2012)

Effect of vitamin A supplementation in women of reproductive age on cause-specific early and late infant mortality in rural Ghana: ObaapaVitA double-blind, cluster-randomised, placebo-controlled trial
por: Edmond, Karen, et al.
Publicado: (2012)

Do pacifiers increase the risk of nosocomial diarrhoea? A cohort study
por: Sette, Gabriela Cunha Schechtman, et al.
Publicado: (2012)

The apparent breastfeeding paradox in very preterm infants: relationship between breast feeding, early weight gain and neurodevelopment based on results from two cohorts, EPIPAGE and LIFT
por: Rozé, Jean-Christophe, et al.
Publicado: (2012)

Dyskeratosis congenita and the DNA damage response
por: Kirwan, Michael, et al.
Publicado: (2011)

Birth outcomes for African and Caribbean babies in England and Wales: retrospective analysis of routinely collected data
por: Datta-Nemdharry, Preeti, et al.
Publicado: (2012)

Family-based behavioural intervention programme for obese children: a feasibility study
por: Teder, Marie, et al.
Publicado: (2012)

Extensively hydrolysed casein formula supplemented with Lactobacillus rhamnosus GG maintains hypoallergenic status: randomised double-blind, placebo-controlled crossover trial
por: Muraro, Antonella, et al.
Publicado: (2012)

Familial factors and child characteristics as predictors of injuries in toddlers: a prospective cohort study
por: Myhre, Mia Cathrine, et al.
Publicado: (2012)

Bacteraemia in Malawian neonates and young infants 2002–2007: a retrospective audit
por: Gwee, Amanda, et al.
Publicado: (2012)

Reactions of Norwegian children with severe egg allergy to an egg-containing influenza A (H1N1) vaccine: a retrospective audit
por: Forsdahl, Bård Anders
Publicado: (2012)

Unidentified Chronic Fatigue Syndrome/myalgic encephalomyelitis (CFS/ME) is a major cause of school absence: surveillance outcomes from school-based clinics
por: Crawley, Esther M, et al.
Publicado: (2011)

Lifestyle counselling targeting infant's mother during the child's first year and offspring weight development until 4 years of age: a follow-up study of a cluster RCT
por: Mustila, Taina, et al.
Publicado: (2012)

Carers’ perspectives on the presentation of community-acquired pneumonia and empyema in children: a case series
por: Crocker, Joanna C, et al.
Publicado: (2012)

Cause-specific infant mortality in a population-based Swedish study of term and post-term births: the contribution of gestational age and birth weight
por: Altman, Maria, et al.
Publicado: (2012)

Myocardial performance assessment in neonates by one-segment strain and strain rate analysis by tissue Doppler - a quality improvement cohort study
por: Nestaas, Eirik, et al.
Publicado: (2012)

Adverse drug reaction-related admissions in paediatrics, a prospective single-centre study
por: Posthumus, Anke A G, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_i7g6daq4ghbhqhifo68bfaioou