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Validation of anti-aging drugs by treating age-related diseases

Humans die from age-related diseases, which are deadly manifestations of the aging process. In order to extend life span, an anti-aging drug must delay age-related diseases. All together age-related diseases are the best biomarker of aging. Once a drug is used for treatment of any one chronic diseas...

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Autor principal: Blagosklonny, Mikhail V.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806014/
https://www.ncbi.nlm.nih.gov/pubmed/20157517
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author Blagosklonny, Mikhail V.
author_facet Blagosklonny, Mikhail V.
author_sort Blagosklonny, Mikhail V.
collection PubMed
description Humans die from age-related diseases, which are deadly manifestations of the aging process. In order to extend life span, an anti-aging drug must delay age-related diseases. All together age-related diseases are the best biomarker of aging. Once a drug is used for treatment of any one chronic disease, its effect against other diseases (atherosclerosis, cancer, prostate enlargement, osteoporosis, insulin resistance, Alzheimer's and Parkinson's diseases, age-related macular degeneration) may be evaluated in the same group of patients. If the group is large, then the anti-aging effect could be validated in a couple of years. Startlingly, retrospective analysis of clinical and preclinical data reveals four potential anti-aging modalities.
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spelling pubmed-28060142010-02-12 Validation of anti-aging drugs by treating age-related diseases Blagosklonny, Mikhail V. Aging (Albany NY) Review Humans die from age-related diseases, which are deadly manifestations of the aging process. In order to extend life span, an anti-aging drug must delay age-related diseases. All together age-related diseases are the best biomarker of aging. Once a drug is used for treatment of any one chronic disease, its effect against other diseases (atherosclerosis, cancer, prostate enlargement, osteoporosis, insulin resistance, Alzheimer's and Parkinson's diseases, age-related macular degeneration) may be evaluated in the same group of patients. If the group is large, then the anti-aging effect could be validated in a couple of years. Startlingly, retrospective analysis of clinical and preclinical data reveals four potential anti-aging modalities. Impact Journals LLC 2009-03-28 /pmc/articles/PMC2806014/ /pubmed/20157517 Text en Copyright: ©2009 Blagosklonny. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Blagosklonny, Mikhail V.
Validation of anti-aging drugs by treating age-related diseases
title Validation of anti-aging drugs by treating age-related diseases
title_full Validation of anti-aging drugs by treating age-related diseases
title_fullStr Validation of anti-aging drugs by treating age-related diseases
title_full_unstemmed Validation of anti-aging drugs by treating age-related diseases
title_short Validation of anti-aging drugs by treating age-related diseases
title_sort validation of anti-aging drugs by treating age-related diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806014/
https://www.ncbi.nlm.nih.gov/pubmed/20157517
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