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Aging of the inceptive cellular population: the relationship between stem cells and aging

The average life expectancy worldwide has about doubled and the global population has increased six fold over the past century. With improving health care in the developed world there is a proportional augmentation in the treatment necessary for elderly patients occasioning the call for increased re...

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Detalles Bibliográficos
Autores principales: Symonds, Catherine E., Galderisi, Umberto, Giordano, Antonio
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806020/
https://www.ncbi.nlm.nih.gov/pubmed/20157525
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author Symonds, Catherine E.
Galderisi, Umberto
Giordano, Antonio
author_facet Symonds, Catherine E.
Galderisi, Umberto
Giordano, Antonio
author_sort Symonds, Catherine E.
collection PubMed
description The average life expectancy worldwide has about doubled and the global population has increased six fold over the past century. With improving health care in the developed world there is a proportional augmentation in the treatment necessary for elderly patients occasioning the call for increased research in the area of aging and age-related diseases. The manifestation of this research has been focalized on the causative cellular processes and molecular mechanisms involved. Here we will discuss the efforts of this research in the area of stem cells, delving into the regulatory mechanisms and how their de-regulation could be attributed to aging and age-related diseases.
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spelling pubmed-28060202010-02-12 Aging of the inceptive cellular population: the relationship between stem cells and aging Symonds, Catherine E. Galderisi, Umberto Giordano, Antonio Aging (Albany NY) Review The average life expectancy worldwide has about doubled and the global population has increased six fold over the past century. With improving health care in the developed world there is a proportional augmentation in the treatment necessary for elderly patients occasioning the call for increased research in the area of aging and age-related diseases. The manifestation of this research has been focalized on the causative cellular processes and molecular mechanisms involved. Here we will discuss the efforts of this research in the area of stem cells, delving into the regulatory mechanisms and how their de-regulation could be attributed to aging and age-related diseases. Impact Journals LLC 2009-04-02 /pmc/articles/PMC2806020/ /pubmed/20157525 Text en Copyright: ©2009 Symonds et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Symonds, Catherine E.
Galderisi, Umberto
Giordano, Antonio
Aging of the inceptive cellular population: the relationship between stem cells and aging
title Aging of the inceptive cellular population: the relationship between stem cells and aging
title_full Aging of the inceptive cellular population: the relationship between stem cells and aging
title_fullStr Aging of the inceptive cellular population: the relationship between stem cells and aging
title_full_unstemmed Aging of the inceptive cellular population: the relationship between stem cells and aging
title_short Aging of the inceptive cellular population: the relationship between stem cells and aging
title_sort aging of the inceptive cellular population: the relationship between stem cells and aging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806020/
https://www.ncbi.nlm.nih.gov/pubmed/20157525
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