P66Shc signals to age

Oxygen metabolism is thought to impact on aging through the formation of reactive oxygen species (ROS) that are supposed to damage biological molecules. The study of p66(Shc), a crucial regulator of ROS level involved in aging dysfunction, suggests that the incidence of degenerative disease and long...

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Detalles Bibliográficos
Autores principales: Trinei, Mirella, Berniakovich, Ina, Beltrami, Elena, Migliaccio, Enrica, Fassina, Ambrogio, Pelicci, PierGiuseppe, Giorgio, Marco
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806035/
https://www.ncbi.nlm.nih.gov/pubmed/20157533
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author Trinei, Mirella
Berniakovich, Ina
Beltrami, Elena
Migliaccio, Enrica
Fassina, Ambrogio
Pelicci, PierGiuseppe
Giorgio, Marco
author_facet Trinei, Mirella
Berniakovich, Ina
Beltrami, Elena
Migliaccio, Enrica
Fassina, Ambrogio
Pelicci, PierGiuseppe
Giorgio, Marco
author_sort Trinei, Mirella
collection PubMed
description Oxygen metabolism is thought to impact on aging through the formation of reactive oxygen species (ROS) that are supposed to damage biological molecules. The study of p66(Shc), a crucial regulator of ROS level involved in aging dysfunction, suggests that the incidence of degenerative disease and longevity are determined by a specific signaling function of ROS other than their unspecific damaging property.
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spelling pubmed-28060352010-02-12 P66Shc signals to age Trinei, Mirella Berniakovich, Ina Beltrami, Elena Migliaccio, Enrica Fassina, Ambrogio Pelicci, PierGiuseppe Giorgio, Marco Aging (Albany NY) Review Oxygen metabolism is thought to impact on aging through the formation of reactive oxygen species (ROS) that are supposed to damage biological molecules. The study of p66(Shc), a crucial regulator of ROS level involved in aging dysfunction, suggests that the incidence of degenerative disease and longevity are determined by a specific signaling function of ROS other than their unspecific damaging property. Impact Journals LLC 2009-06-05 /pmc/articles/PMC2806035/ /pubmed/20157533 Text en Copyright: ©2009 Trinei et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Trinei, Mirella
Berniakovich, Ina
Beltrami, Elena
Migliaccio, Enrica
Fassina, Ambrogio
Pelicci, PierGiuseppe
Giorgio, Marco
P66Shc signals to age
title P66Shc signals to age
title_full P66Shc signals to age
title_fullStr P66Shc signals to age
title_full_unstemmed P66Shc signals to age
title_short P66Shc signals to age
title_sort p66shc signals to age
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806035/
https://www.ncbi.nlm.nih.gov/pubmed/20157533
work_keys_str_mv AT trineimirella p66shcsignalstoage
AT berniakovichina p66shcsignalstoage
AT beltramielena p66shcsignalstoage
AT migliaccioenrica p66shcsignalstoage
AT fassinaambrogio p66shcsignalstoage
AT peliccipiergiuseppe p66shcsignalstoage
AT giorgiomarco p66shcsignalstoage

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