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What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence

Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, targets the retinal pigment epithelium (RPE), a monolayer of cells at the back of the eye. As AMD progresses, it can develop into two distinct forms of late AMD: "dry," atrophic AMD, characterized by RPE...

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Detalles Bibliográficos
Autores principales: Zhu, DanHong, Deng, Xuemei, Xu, Jing, Hinton, David R
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806048/
https://www.ncbi.nlm.nih.gov/pubmed/20157553

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