A novel intermembrane space–targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding

Mia40 imports Cys-containing proteins into the mitochondrial intermembrane space (IMS) by ensuring their Cys-dependent oxidative folding. In this study, we show that the specific Cys of the substrate involved in docking with Mia40 is substrate dependent, the process being guided by an IMS-targeting...

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Detalles Bibliográficos
Autores principales: Sideris, Dionisia P., Petrakis, Nikos, Katrakili, Nitsa, Mikropoulou, Despina, Gallo, Angelo, Ciofi-Baffoni, Simone, Banci, Lucia, Bertini, Ivano, Tokatlidis, Kostas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806287/
https://www.ncbi.nlm.nih.gov/pubmed/20026652
http://dx.doi.org/10.1083/jcb.200905134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806287/
https://www.ncbi.nlm.nih.gov/pubmed/20026652
http://dx.doi.org/10.1083/jcb.200905134

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