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A novel intermembrane space–targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding
Mia40 imports Cys-containing proteins into the mitochondrial intermembrane space (IMS) by ensuring their Cys-dependent oxidative folding. In this study, we show that the specific Cys of the substrate involved in docking with Mia40 is substrate dependent, the process being guided by an IMS-targeting...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806287/ https://www.ncbi.nlm.nih.gov/pubmed/20026652 http://dx.doi.org/10.1083/jcb.200905134 |