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Regulation of Akt(ser473) phosphorylation by Choline kinase in breast carcinoma cells
BACKGROUND: The serine/threonine kinase PKB/Akt plays essential role in various cellular processes including cell growth and proliferation, metabolism and cell survival. The importance of the Akt pathway is highlighted by the mutation of various components of the pathway such as the PTEN and PI3-kin...
Autores principales: | Chua, Boon Tin, Gallego-Ortega, David, de Molina, Ana Ramirez, Ullrich, Axel, Lacal, Juan Carlos, Downward, Julian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806310/ https://www.ncbi.nlm.nih.gov/pubmed/20042122 http://dx.doi.org/10.1186/1476-4598-8-131 |
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