Cargando…
ISWI is a RanGTP-dependent MAP required for chromosome segregation
Production of RanGTP around chromosomes induces spindle assembly by activating nuclear localization signal (NLS)–containing factors. Here, we show that the NLS protein ISWI, a known chromatin-remodeling ATPase, is a RanGTP-dependent microtubule (MT)-associated protein. Recombinant ISWI induces MT nu...
Autores principales: | Yokoyama, Hideki, Rybina, Sofia, Santarella-Mellwig, Rachel, Mattaj, Iain W., Karsenti, Eric |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806316/ https://www.ncbi.nlm.nih.gov/pubmed/20008562 http://dx.doi.org/10.1083/jcb.200906020 |
Ejemplares similares
-
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
por: Yokoyama, Hideki, et al.
Publicado: (2008) -
A Novel Class of RanGTP Binding Proteins
por: Görlich, Dirk, et al.
Publicado: (1997) -
RanGTP and CLASP1 cooperate to position the mitotic spindle
por: Bird, Stephen L., et al.
Publicado: (2013) -
RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization
por: Mori, Masashi, et al.
Publicado: (2021) -
Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells
por: Hasegawa, Keisuke, et al.
Publicado: (2013)