Extensive analysis of D-J-C arrangements allows the identification of different mechanisms enhancing the diversity in sheep T cell receptor β-chain repertoire

BACKGROUND: In most species of mammals, the TRB locus has the common feature of a library of TRBV genes positioned at the 5'- end of two in tandem aligned D-J-C gene clusters, each composed of a single TRBD gene, 6-7 TRBJ genes and one TRBC gene. An enhancer located at the 3'end of the las...

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Detalles Bibliográficos
Autores principales: Di Tommaso, Silvia, Antonacci, Rachele, Ciccarese, Salvatrice, Massari, Serafina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806336/
https://www.ncbi.nlm.nih.gov/pubmed/20047680
http://dx.doi.org/10.1186/1471-2164-11-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806336/
https://www.ncbi.nlm.nih.gov/pubmed/20047680
http://dx.doi.org/10.1186/1471-2164-11-3

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