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Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity
TRPM2 is a Ca(2+)-permeable nonselective cation channel that plays important roles in oxidative stress–mediated cell death and inflammation processes. However, how TRPM2 is regulated under physiological and pathological conditions is not fully understood. Here, we report that both intracellular and...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806426/ https://www.ncbi.nlm.nih.gov/pubmed/19917732 http://dx.doi.org/10.1085/jgp.200910254 |