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GATA-3 is required for early T lineage progenitor development
Most T lymphocytes appear to arise from very rare early T lineage progenitors (ETPs) in the thymus, but the transcriptional programs that specify ETP generation are not completely known. The transcription factor GATA-3 is required for the development of T lymphocytes at multiple late differentiation...
Autores principales: | Hosoya, Tomonori, Kuroha, Takashi, Moriguchi, Takashi, Cummings, Dustin, Maillard, Ivan, Lim, Kim-Chew, Engel, James Douglas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806453/ https://www.ncbi.nlm.nih.gov/pubmed/19934022 http://dx.doi.org/10.1084/jem.20090934 |
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