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c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells
During thymopoiesis, a unique program of gene expression promotes the development of CD4 regulatory T (T reg) cells. Although Foxp3 maintains a pattern of gene expression necessary for T reg cell function, other transcription factors are emerging as important determinants of T reg cell development....
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806473/ https://www.ncbi.nlm.nih.gov/pubmed/19995950 http://dx.doi.org/10.1084/jem.20091411 |
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por Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances, Gerondakis, Steve
Publicado 2010
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Publicado 2010
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Texto