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The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

BACKGROUND: Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic cell death of tumor cells in vitro as well as in vivo....

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Detalles Bibliográficos
Autores principales:	Moreira, José Manuel Afonso, Scheipers, Peter, Sørensen, Poul
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280656/ https://www.ncbi.nlm.nih.gov/pubmed/14606959 http://dx.doi.org/10.1186/1471-2407-3-30

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