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Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement
Sister chromatid separation at anaphase is triggered by cleavage of the cohesin subunit Scc1, which is mediated by separase. Centriole disengagement also requires separase. This dual role of separase permits concurrent control of these events for accurate metaphase to anaphase transition. Although t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806580/ https://www.ncbi.nlm.nih.gov/pubmed/19948489 http://dx.doi.org/10.1083/jcb.200906019 |