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Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates

Ubiquitin (Ub) modification of proteins plays a prominent role in the regulation of multiple cell processes, including endoplasmic reticulum–associated degradation (ERAD). Until recently, ubiquitination of substrates was thought to occur only via isopeptide bonds, typically to lysine residues. Sever...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoli, Herr, Roger A., Rabelink, Martijn, Hoeben, Rob C., Wiertz, Emmanuel J.H.J., Hansen, Ted H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806592/
https://www.ncbi.nlm.nih.gov/pubmed/19951915
http://dx.doi.org/10.1083/jcb.200908036