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Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3(+) inducible regulatory T cells

Forkhead box P3 (FOXP3)(+)CD4(+)CD25(+) inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. In this study, we show that the transforming growth factor-β (TGF-β) induces the expression of the Runt-related transcription factors RUNX1 and RUNX3 in CD4(+) T...

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Detalles Bibliográficos
Autores principales:	Klunker, Sven, Chong, Mark M.W., Mantel, Pierre-Yves, Palomares, Oscar, Bassin, Claudio, Ziegler, Mario, Rückert, Beate, Meiler, Flurina, Akdis, Mübeccel, Littman, Dan R., Akdis, Cezmi A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806624/ https://www.ncbi.nlm.nih.gov/pubmed/19917773 http://dx.doi.org/10.1084/jem.20090596

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