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DNA damage signalling prevents deleterious telomere addition at DNA breaks

The response to DNA damage involves regulation of multiple essential processes to maximize the accuracy of DNA damage repair and cell survival 1. Telomerase has the potential to interfere with repair by inappropriately adding telomeres to DNA breaks. It was unknown whether cells modulate telomerase...

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Detalles Bibliográficos
Autores principales: Makovets, Svetlana, Blackburn, Elizabeth H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806817/
https://www.ncbi.nlm.nih.gov/pubmed/19838171
http://dx.doi.org/10.1038/ncb1985