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A model of tripeptidyl-peptidase I (CLN2), a ubiquitous and highly conserved member of the sedolisin family of serine-carboxyl peptidases
BACKGROUND: Tripeptidyl-peptidase I, also known as CLN2, is a member of the family of sedolisins (serine-carboxyl peptidases). In humans, defects in expression of this enzyme lead to a fatal neurodegenerative disease, classical late-infantile neuronal ceroid lipofuscinosis. Similar enzymes have been...
Autores principales: | Wlodawer, Alexander, Durell, Stewart R, Li, Mi, Oyama, Hiroshi, Oda, Kohei, Dunn, Ben M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC280685/ https://www.ncbi.nlm.nih.gov/pubmed/14609438 http://dx.doi.org/10.1186/1472-6807-3-8 |
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